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ORIGINAL ARTICLE12-12-2025
Influence of therapeutic play on salivary cortisol levels in children undergoing venipuncture
Revista Brasileira de Enfermagem. 2025;78:e20240636
Abstract
ORIGINAL ARTICLEInfluence of therapeutic play on salivary cortisol levels in children undergoing venipuncture
Revista Brasileira de Enfermagem. 2025;78:e20240636
DOI 10.1590/0034-7167-2024-0636
Views12See moreABSTRACT
Objectives:
to investigate the influence of Instructional Therapeutic Play on salivary cortisol levels in children undergoing peripheral venipuncture.
Methods:
randomized controlled clinical trial, allocated into two groups: Intervention and Control, conducted in pediatric inpatient units, children’s emergency rooms, and outpatient clinics of two hospitals in the city of São Paulo. A sample of 52 children, both genders, aged between 3 and 12 years, underwent venipuncture and were able to play. Data were analyzed using descriptive and inferential statistics with a 5% significance level and a 95% confidence interval.
Results:
cortisol levels decreased in both groups, but less so among children who did not receive the toy intervention, remaining lower for those who did receive the intervention, and among those who were successfully punctured on the first attempt.
Conclusions:
although the null hypothesis was confirmed in this study, the use of Therapeutic Play for stress relief is recommended.
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REVIEW12-08-2025
Nursing practices and complications associated with peripheral catheterization for outpatient antineoplastic therapy: scoping review
Revista Brasileira de Enfermagem. 2025;78:e20240528
Abstract
REVIEWNursing practices and complications associated with peripheral catheterization for outpatient antineoplastic therapy: scoping review
Revista Brasileira de Enfermagem. 2025;78:e20240528
DOI 10.1590/0034-7167-2024-0528
Views7See moreABSTRACT
Objectives:
to map the evidence on nursing practices related to outpatient antineoplastic therapy using peripheral intravenous catheters and to identify the complications associated with the use of this device.
Methods:
this is a scoping review conducted according to the JBI methodology. The selection process was carried out independently and blindly by two reviewers.
Results:
a total of 1,287 publications were retrieved, and 16 studies were ultimately included. The identified practices were related to responsibility for the procedure; infection prevention and biosafety; selection of the puncture site; choice of the puncture device; skin preparation; venous puncture; access maintenance; catheter dressing and stabilization; and device removal and disposal. The most frequently reported complications were phlebitis, edema, pain, burning sensation, extravasation, and bloodstream infection.
Conclusions:
this study mapped peripheral intravenous catheterization practices for outpatient antineoplastic therapy into nine categories. The most common complications included phlebitis, edema, pain, burning sensation, extravasation, and bloodstream infection.



